According to research conducted by James
Hays, M.D., of the National Naval Medical
Center in Bethesda, Md., and his research
team, a low-carb, high-fat diet regulated
blood sugar and eliminated hypoglycemic
symptoms in type II diabetics. Findings
were submitted at the 81st Annual Meeting
of the Endocrine Society last June and
are being reviewed for publication.


Koledzy lekarze prosza o publikacje,
Moze ten zespol cos opublikuje, jak widac zaproszono ich do tego.



a narazie abstract z Toronto | June 21-24
The Endocrine Society's 82nd
Annual Meeting




[2339] Carbohydrate Restricted High-Fat Non-Ketotic Diet Improves
Polycystic Ovary Syndrome.
J Hays, R Gorman, B McGuirk, R Fienberg, J C Wood, K MM Shakir
Medicine, Milcreek Medical Center,
Wilmington, DE; Endocrinology, National Naval Medical Center,
Bethesda, MD





Polycystic Ovary Syndrome (PCOS), a complex disorder, is associated with
insulin resistance.
Recent studies show that insulin sensitizing drugs may improve the
clinical features of PCOS. In this
report we describe the favorable effect of a high-fat diet in this
syndrome. Eighteen women ages
21-43 yrs (33.9?1.6 Mean?SEM)8 of whom desired fertility, were
referred with a diagnosis of
PCOS.Four complained of hirsutism, while 8 complained of
oligomenorrhea. Pts were placed on a
high-fat diet (50% fat, 30% carbohydrate, 20% protein). After 3
months significant weight loss was
associated with increased fasting glucose/insulin ratios and lowered
serum triglyceride levels. These
effects continued to persist even after 6 mos. Three of eight
desiring fertility became pregnant. Two
responded to lower doses of clomifene. One became pregnant without
drugs after previously failing
IVF x 2. Three of 4 reported mild to moderate subjective improvement
in hirsutism. Seven of 8
reported regular menses.
PCOS is associated with hyperinsulinemia. The diet resulted in weight
loss and improved the
glucose/insulin ratio with resultant improved insulin resistance.
This was associated with improved
symptoms of PCOS without deterioration of serum lipids. A high-fat
non-ketotic diet, by improving
insulin resistance, may be beneficial in pts with PCOS.
n=18, *BMI = Body Mass Index
** FBG/Ins = Fasting Blood Glucose/Fasting Insulin Level
TIME 0 MONTHS 3 MONTHS 6 MONTHS p VALUES
BMI* 36.1?2.2 33.7?2.2 33.2?2.8 <0.001
FBG/Ins** 5.1?0.7 8.1?0.7 9.3?1.0 <0.001
Chol 211?11 200?11 205?10 0.06
TG 140?22 107?16 99?11 0.02
HDL 55?3 58?3 55?3 0.09






Przepraszam ze po angielsku, ale niektorzy koledzy domagali sie wynikow
badan, a te jak na razie sa tylko w takim narzeczu