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From: "Jacek" <o...@p...com>
Newsgroups: pl.sci.medycyna
Subject: Re: Od pieciu lat jestem na zywieniu Optymalnym Jana Kwasniewskiego
Date: Mon, 4 Nov 2002 13:30:00 +0100
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Ukryj nagłówki
> Posiłkujac sie ww. "podręcznikiem", można wiele pokazać.
Skoro nie podoba sie kilku z was Harper to moze takie artykuly:
"Original article
Bactericidal effects of fatty acids and monoglycerides on
Helicobacter pylori
Gudmundur Bergsson a,*, O´ lafur Steingrý´msson b, Halldor Thormar a
a Institute of Biology, University of Iceland, Grensasvegur 12, 108
Reykjavik, Iceland
b Department of Microbiology, University Hospital, Reykjavik, Iceland
Received 24 January 2002; accepted 17 April 2002
Abstract
The susceptibility of Salmonella spp., Escherichia coli and Helicobacter
pylori to fatty acids and monoglycerides was studied.
None of the lipids showed significant antibacterial activity against
Salmonella spp. and E. coli but eight of 12 lipids tested showed
high activity against H. pylori , monocaprin and monolaurin being the most
active. The high activity of monoglycerides against H.
pylori suggests that they may be useful as active ingredients in
pharmaceutical formulations.
# 2002 Elsevier Science B.V. and International Society of Chemotherapy. All
rights reserved.
International Journal of Antimicrobial Agents 20 (2002) 258/262
www.isochem.org"
Wynika z niego ni mniej ni wiecej jak tylko to ze przyczyna bujnego rozwoju
Helicobacter Pyroli jest niskotluszczowa dieta. Moze to doskonale tlumaczyc
wyleczenia wrzodowcow za pomoca diety Sippiego, polegajacej na piciu 0,5
litra smietany kremowki dziennie, ona jest bogata wlasnie w te nienajdluzsze
kwasy tluszczowe.
Albo taki:
"
Killing of Chlamydia trachomatis by Novel Antimicrobial Lipids
Adapted from Compounds in Human Breast Milk
M. F. LAMPE,1* L. M. BALLWEBER,1 C. E. ISAACS,2 D. L. PATTON,1 AND W. E.
STAMM1
University of Washington, Seattle, Washington,1 and NYS Institute for Basic
Research, Staten Island, New York2
Received 8 September 1997/Returned for modification 22 December
1997/Accepted 5 March 1998
The development of new methods for prevention of sexually transmitted
Chlamydia trachomatis infection is
a top public health priority. Topical self-administered vaginal microbicides
represent one such approach in
which the organism is eradicated at the time of initial exposure. To this
end, we examined the activity of five
synthetic lipids adapted from naturally occurring compounds found in human
breast milk. C. trachomatis
serovar D or F elementary bodies were added to serial dilutions of the
lipids and incubated for various times.
Aliquots were then cultured in monolayers of McCoy cells, and inclusions
were counted. A 7.5 mM concentration
of 2-O-octyl-sn-glycerol completely prevented growth of C. trachomatis after
120 min of contact with the
organism. The remaining lipids, 1-O-octyl-, 1-O-heptyl-, 2-O-hexyl-, and
1-O-hexyl-sn-glycerol, showed less
activity. On electron microscopic examination, the lipids were shown to have
disrupted the chlamydial inner
membrane, allowing leakage of the cytoplasmic contents from the cell. Lipid
activity was unaffected by the
presence of 10% human blood or alterations in pH from 4.0 to 8.0, conditions
reflecting those sometimes found
in the vagina. Our results suggest that these lipids, especially
2-O-octyl-sn-glycerol, may be effective as topical
microbicides in preventing the transmission of C. trachomatis. Further
efficacy and toxicity studies with these
lipids and assessment of their activity against other sexually transmitted
disease pathogens are in progress."
Kwasy tluszczowe rowniez dzialaja bakteriobojczo na takie choroby jak
weneryczne, I chodzi tu o tluszcze obecne w mleku matki. Pokazuje to jak
wazne jest naturalne karmienie dzieci, mozna podejzewac ze na inne bakterie
tez to dziala.
No i ostatni na dzis:
"
Antimicrobial activity of lipids added
to human milk, infant formula, and
bovine milk
Charles E. Isaacs, Richard E. Litov,*t and Halldor ThormarS
New York State Institute of Basic Research in Developmental Disabilities,
Staten Island, NY USA;
and *Mead Johnson Research Center, Evansville, IN USA; SInstitute of
Biology, University of
Iceland, Reykjavik, Iceland
Lipids previously shown to have antiviral and antibacterial activity in
buffers were added to human milk, bovine
milk, and infant formulas to determine whether increased protection from
infection could be provided to infants
as part of their diet. Fatty acids and monoglycerides with chain lengths
varying from 8 to 12 carbons were found
to be more strongly antiviral and antibacterial when added to milk and
formula than long chain monoglycerides.
Lipids added to milk and formula inactivated a number of pathogens including
respiratory syncytial virus (RSV),
herpes simplex virus type 1 (HSV-I), Haemophilus influenzae, and Group B
streptococcus. The results presented
in this study suggest that increased protection from infection may be
provided to infants at mucosal surfaces,
prior to the digestion of milk and formula triglycerides, by the addition of
antimicrobial medium chain mono-
glycerides to an infant's diet. (J. Nutr. Biochem. 6:362-366, 1995.)"
Niestety nie wiem ile takich kwasow tluszczowych jest w masle? ale z tego co
wiem to jest ono bogate w sredniolancuchowe kwasy tluszczowe, w
przeciwienstwie do margaryny, ktora ma dlugolancuchowe, a wiec nieaktywne
antywirusowo i antybakteryjnie tluszcze.
Pozdrawiam
Jacek
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