> sprawdzilem w sieci, zadna ze stron nie wspomina w ogole alkoholu
>
> boria
>
>
> Użytkownik "Daniel Sereno" <c...@w...pl> napisał w wiadomości
> news:9n0kgj$o13$1@news.onet.pl...
> > witam!!!
> >
> > mam pytanie: czy przy leczeniu cipramilem mozna pic alkohol? ulotka nic
> nie
> > mowi ale wole sie upewnic
> > dziekuje
> >
> > ds
> >
> >
>
>

Nalezaloby sprawdzac pod prawidlowa, miedzynarodowa nazwa : citalopram.
Jest circa 140 pozycji pismiennictwa w tym zakresie.
Citalopram jest uzywany rowniez do leczenia alkoholizmu, wiec nie powinno byc
klopotow z alkoholem.

Problem jest jeden : u szczorow powoduje on czsami powstanie rekcji i to
takiej ,ktora nie chce godzinami ustapic (mimo braku samicy w okolicy).

Nie wiem jak sobie poradzisz w takiej sytuacji... :-))))


Pozdrawiam, wiecej sie juz nie bede wypowiadal

dradam

==============================================

Alcohol 2001 May;24(1):15-23
Further investigation of citalopram on alcohol consumption in heavy drinkers:
responsiveness

possibly linked to the DRD2 A2/A2 genotype.
Eriksson M, Berggren U, Blennow K, Fahlke C, Balldin J.
Institute of Clinical Neuroscience, Department of Psychiatry and
Neurochemistry, Goteborg

University, Sahlgren University Hospital/Molndal, SE-431 80 Molndal, Sweden


Drug Alcohol Depend 2001 Aug 1;63(3):263-267 Related Articles, Books, LinkOut
Relationship between central serotonergic neurotransmission and reduction in
alcohol intake

by citalopram.
Berggren U, Eriksson M, Fahlke C, Balldin J.
Department of Psychiatry and Neurochemistry, Institute of Clinical
Neuroscience, Goteborg

University, Sahlgrenska University Hospital/Molndal, SE-43180, Molndal, Sweden


Alcohol Alcohol Suppl 1996 Mar;1:69-75 Related Articles, Books, LinkOut
Use of serotonin (5-hydroxytryptamine) reuptake inhibitors in the treatment of
alcoholism.
Lejoyeux M.
Department of Psychiatry, Groupe Hospitalier Bichat Claude Bernard, Paris,
France.
Animal studies have shown that alcohol consumption is reduced when serotonin

(5-hydroxytryptamine, 5-HT) levels are increased in the central nervous system.
Similarly,

studies of alcohol-dependent human subjects have shown that treatment with 5-HT
reuptake

inhibitors (i.e. zimeldine, citalopram, fluoxetine, and fluvoxamine) decreases
the desire to

drink alcohol and improves symptoms of alcohol-related anxiety and depression
in patients

who have undergone detoxification. However, not all studies have shown them to
be an

effective treatment to help maintain recovery in alcohol dependence. The exact
mechanisms of

action of the 5-HT reuptake inhibitors are not yet fully understood and
additional studies

are needed. However, at this time, the 5-HT reuptake inhibitors may be
effective

pharmacotherapies for alcohol-related depression.
PMID: 9845041 [PubMed - indexed for MEDLINE]

Alcohol 1998 Nov;16(4):295-303 Related Articles, Books, LinkOut
Citalopram as an inhibitor of voluntary ethanol intake in the male rat.
Hedlund L, Wahlstrom G.
Department of Pharmacology, Umea University, Sweden.
Psychological dependence was induced in rats by a 1-year intermittent exposure
to

intoxicating doses of ethanol, and recorded by the rat's ability to later take
the same dose

of ethanol independent of the offered concentration. Citalopram (10 or 40
mg/kg/day) was

given for 3 weeks with ethanol available only the first and the last day; 10
mg/kg had no

effect. On the first treatment day 40 mg/kg decreased ethanol intake. On the
last treatment

day 40 mg/kg had no effect. The following week the ethanol intake was higher
than before the

treatment in the 40 mg/kg group. During the four posttreatment weeks the
ethanol intake of

the 40 mg/kg group dropped significantly. Citalopram was retested 18 weeks
after the first

treatment during 1 week, with continuous access to ethanol; 10 mg/kg had no
effect and 40

mg/kg decreased ethanol intake at day 1, reaching a minimum in day 3. A
tolerance to this

effect was seen at the end of the week. Thus, in this model an acute dose of
citalopram can

decrease ethanol intake, but tolerance to this effect develops when citalopram
is given both

with and without access to ethanol.

PMID: 9818981 [PubMed - indexed for MEDLINE]

Eur J Pharmacol 1987 Mar 31;135(3):279-287 Related Articles, Books
Drug-induced penile erections in rats: indications of serotonin1B receptor
mediation.
Berendsen HH, Broekkamp CL.
The induction of penile erections by a variety of compounds with a direct or
indirect effect

on serotonin (5HT) receptors was investigated in rats. L-5-Hydroxy-tryptophan
(L-5HTP)

induced penile erections when co-administered with nialamide and the peripheral

decarboxylase inhibitor benserazide, indicating that the site of action for
inducing penile

erections is within the central nervous system. Penile erections were also
induced by the

5HT uptake inhibitors zimelidine, fluoxetine, citalopram, Org 6997, by the 5HT-
releasing

agent fenfluramine and by the putative 5-HT1B receptor agonist

1-(3'-chlorophenyl)-piperazine (mCPP). The 5HT1A-agonist

8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT) did not induce penile
erections. The

less selective 5HT receptor agonists 5-methoxy-N,N-dimethyl-tryptamine
(5MeODMT),

5-methoxytryptamine (5MeOT), dl-lysergic acid diethylamide (LSD) and Ru 24969
were also

ineffective. Induction of penile erections by quipazine appeared only when this
compound was

co-administered with the 5HT2 receptor antagonist pirenperone. Receptor
antagonists were

tested against penile erections induced by Org 6997. The beta-adrenoceptor
antagonists that

also have 5HT1 antagonistic properties, (S)-pindolol and dl-propranolol,
antagonized Org

6997-induced penile erections but butoxamine and metoprolol did not. Spiperone
and

pirenperone in doses selective for 5HT1A and 5HT2 receptors respectively were
also inactive.

Haloperidol, 0.46 mg/kg, partially attenuated penile erections induction. The
data are

discussed in the light of the hypothesis that penile erections induction by

serotonin-mimetic compounds is mediated by 5HT1B receptors in the striatum.

PMID: 3495447 [PubMed - indexed for MEDLINE]



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