Paolo Pelini:Lung cancer and subsequent metastasis (small cell carcinoma, non-small
cell carcinoma) are caused by the bacterium Pseudomonas. This microorganism is able
to promote by means of a number of substances, and secondary metabolites produced by
it from a part of the host organism response that induces a series of modifications
and biochemical stimuli that lead to tumorigenesis and metastasis to the next, with
the cell modifications designed to acquire specific properties of metastatic cells as
cell adhesiveness modification that allow cancer cells to break away from the tumor
to which they belong and to adhere to other molecules or cells and phenomena of
angiogenesis. In addition, the bacterium Pseudomonas is able to reshape the immune
response making it ineffective and conducive to the development of metastases as
apoptosis NK-natural killer cells normally deputies to the elimination of cancer
cells.
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