On Fri, 18 Jan 2002, Kaczucha wrote:

> Moglabym prosic o dokladniejszy namiar sprawdzalam w newsach, jednak nic nie
> znalazlam

Jesli chodzi o Ukrain w Medline, to jednak jest to lek eskeperymentalnie
stosowany, co przedstawia pismiennictwo - i to stosowany takze w Polsce.
Wybrane cytaty z Medline:

Interaction between Ukrain and morphine in their ten-day treatment in
mice in the writhing syndrome test.

Jagiello-Wojtowicz E, Kleinrok Z, Nowicky JW,
Chodkowska A, Kubiatowski T, Piper
H.

Department of Pharmacology, Medical Academy,
Lublin, Poland.

The antinociceptive properties of Ukrain and of
morphine in their 10 day treatment in mice were
studied by the writhing syndrome test. It was found
that the antinociceptive action of Ukrain after
10 days of treatment was similar to that of
morphine (0.1 mg/kg s.c.) in the same period. Results
indicate that the combined treatment with Ukrain
and morphine for 10 days completely reduced
their antinociceptive action.

Ukrain (NSC-631570) influences on bone status: a review.

Jablonski M.

Medical University Orthopedic Department, Lublin,
Poland. f...@r...net.pl

Ukrain, a thiophosphoric acid alkaloid derivative
of Chelidonium majus L., was shown to affect
bone tissue metabolism as assessed in densitometric
and biomechanical studies in rats. Its action
could be slightly osteopenic at the highest doses
administered to intact animals for a prolonged
period of time. This phenomenon is possibly related
to Ukrain's inhibitory effect on spontaneous
locomotor activity of treated animals and/or to the
stimulatory effect of the drug on the
osteoclastic activity via the macrophage system. By
far, the most important finding seems to be
the anabolic effect of Ukrain on bone in
ovariectomized rats, which is most probably related to
induced increase in the production of gonadal
hormones, predominantly estrogens. In this regard,
the postmenopausal population of female patients
treated for malignancies with Ukrain (and
obviously the most numerous one) meritis clinical
attention as far as the antiosteoporotic effects of
this drug are concerned.

Publication Types:
Review
Review, Tutorial

PMID: 11345045 [PubMed - indexed for MEDLINE]

Jak widac w osrodku lubelskim - jest nawet email do jednegoz autorow
doniesienia.

Pytanie tylko czy w danej chorobie ten preparat ma szanse zadzialac?
W tym aspekcie nie podoba mi sie strona reklamujaca ten preparat,
poniewaz generalnie w ogole nie zaleca sie reklamowania lekow
przeznaczonych wylacznie do podawania na recepte czy w leczeniu
szpitalnym wsrod pacjentow - zdaje sie, ze to jest zabronione.

Wiekszosc doniesien o Ukrain cytowanych przez Medline jest
autorstwa lekarzy rosyjskich (lub ukrainskich( i publikowanych
najczesciej w jednym czasopismie (chyba nie az tak znanym),
ktorym jest Drugs Exp Clin Res.

P.
----
Piotr Kasztelowicz <P...@a...torun.pl>
[http://www.am.torun.pl/~pekasz]